Topical treatment or prevention of ocular infections
AssigneeInsite Vision Incorporated
InventorsChandler R. Dawson, Lyle M. Bowman
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Abstract
The topical application of an azalide antibiotic such as azithromycin to the eye is useful in treating or preventing ocular infections. In one embodiment, the azalide antibiotic is supplied to the eye in a depot for sustained release. A more convenient dosing regimen can also be provided by the use of an appropriate depot. Furthermore, a composition containing a combination of medicaments is also provided.
Claims62
An aqueous topical ophthalmic composition comprising azithromycin, an anti-inflammatory agent and an ophthalmically acceptable carrier, wherein said topical ophthalmic composition has a pH of 6 to 7.
A process for treating infection in a tissue of an eye, which comprises:
- topically applying an aqueous ophthalmic composition to an eye, wherein said ophthalmic composition comprises azithromycin in an amount effective to treat infection in the tissue of the eye, an anti-inflammatory agent and an ophthalmically acceptable carrier and said ophthalmic composition has a pH of 6 to 7.
An aqueous topical ophthalmic composition comprising azithromycin, an anti-inflammatory agent and an ophthalmically acceptable carrier, wherein said topical ophthalmic composition has a pH of 6 to 7, and wherein said composition is in drop form.
A process for treating infection in a tissue of an eye, which comprises:
- topically applying an aqueous ophthalmic composition to an eye, wherein said ophthalmic composition comprises azithromycin in an amount effective to treat infection in the tissue of the eye, an anti-inflammatory agent and an ophthalmically acceptable carrier and said ophthalmic composition has a pH of 6 to 7 and wherein said composition is in drop form.
Dependencies are inferred from the claim text.