US 7,732,402 B2Granted

Mammalian telomerase

AssigneeGeron Corporation

InventorsBryant Villeponteau, Junli Feng, Walter Funk, William Andrews

Life of this patent

Estimating the term…

Abstract

Nucleic acids comprising the RNA component of a mammalian telomerase are useful as pharmaceutical, therapeutic, and diagnostic reagents.

Claims7

Dependent claims

A method for inhibiting telomerase activity in human cells in vitro, the method comprising the step of contacting the cells in vitro with a polynucleotide comprising a ribozyme in an amount sufficient to inhibit telomerase activity, the ribozyme comprising a nucleotide sequence of 5′UAGGGUUACUGAUGAGUCCGUGAGGACGAAACAAAAAAU-3′ (SEQ ID NO:12) wherein the ribozyme inhibits endogenous telomerase activity in the cell in vitro.

Dependencies are inferred from the claim text.

Facts

Application: 10/359,935Filed 7 Feb 2003 · continuation
Priority: 7 Jul 1994
Published: US 2003/0153076 A114 Aug 2003
Granted: 8 Jun 2010
Term ends: Not estimatedThe source records don’t support an estimate.

Classification26 codes

C12N 15/11
Recombinant DNA-technology: dNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity
A61L 29/041
Macromolecular materials: obtained by reactions only involving carbon-to-carbon unsaturated bonds
A61L 29/14
Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters: materials characterised by their function or physical…
C12N 9/1241
Transferring phosphorus containing groups, e.g. kinases: nucleotidyltransferases

Family

Application08/272,102Parent of this continuation-in-part · filed 7 Jul 1994
Application08/330,123Parent of this continuation-in-part · filed 27 Oct 1994
Application08/472,802Parent of this continuation · filed 7 Jun 1995
Application09/057,351Parent of this continuation · filed 8 Apr 1998
US 2003/0153076 A1Pre-grant publication · published 14 Aug 2003
US 6,548,298 B2Parent of this continuation
US 5,958,680 AParent of this continuation
US 5,583,016 AParent of this continuation-in-part
Application08/472,802Parent of this continuation-in-part
US 2001/0034439 A1Published application
US 7,732,402 B2This patent

From the US filing history. Foreign family members aren’t listed.

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Citations

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Facts

Application

10/359,935Filed 7 Feb 2003 · continuation

Priority

7 Jul 1994

Published

US 2003/0153076 A114 Aug 2003

Granted

8 Jun 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification26 codes

C12N 15/11
Recombinant DNA-technology: dNA or RNA fragments; Modified forms thereof ; Non-coding nucleic acids having a biological activity
A61L 29/041
Macromolecular materials: obtained by reactions only involving carbon-to-carbon unsaturated bonds
A61L 29/14
Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters: materials characterised by their function or physical…
C12N 9/1241
Transferring phosphorus containing groups, e.g. kinases: nucleotidyltransferases

Family

Application08/272,102Parent of this continuation-in-part · filed 7 Jul 1994

Application08/330,123Parent of this continuation-in-part · filed 27 Oct 1994

Application08/472,802Parent of this continuation · filed 7 Jun 1995

Application09/057,351Parent of this continuation · filed 8 Apr 1998

US 2003/0153076 A1Pre-grant publication · published 14 Aug 2003

US 6,548,298 B2Parent of this continuation

US 5,958,680 AParent of this continuation

US 5,583,016 AParent of this continuation-in-part

Application08/472,802Parent of this continuation-in-part

US 2001/0034439 A1Published application

US 7,732,402 B2This patent

From the US filing history. Foreign family members aren’t listed.