Device for the regeneration of tissue, specifically bone regeneration by means of callus distraction
AssigneeCelgen AG
InventorDomonkos Horvath
Life of this patent
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Abstract
The device incorporates a structurally stable membrane (4, 4′, 34, 35) that incorporates a surface (15) to be bonded to a tissue to be regenerated, specifically a vital bone (2, 22, 38, 39). Means (9, 5, 6, 25, 36) are additionally provided whereby the membrane (4, 4′, 24, 35) is movable for the regeneration with a certain pulling force and speed. According to the invention the membrane (4, 4′, 24, 35) has, on its surface facing the tissue or bone, means (16) for the biological anchoring and adhesion for tissue or bone cells. These means (16) for the biological anchoring of tissue cells are specifically bone cells, protein molecules and/or osteoblasts (17), as well as indentations (45, 46, 48) and surface peaks (50) of the membrane.
Claims12
A process for tissue regeneration, in which a membrane that is permeable to the exchange of nutrients is bonded to a tissue or vital bone to be regenerated, wherein a surface of the membrane facing the tissue or bone incorporates means for the biological adhesion of osteoblasts, and the membrane is placed onto the tissue or vital bone at a location to be regenerated, and the membrane is moved away from the tissue or vital bone for distraction at a speed of 0.5 to 2 mm per day.
A process for tissue regeneration comprising:
- placing a membrane, that is permeable to the exchange of nutrients, onto a tissue or vital bone to be regenerated, to bond the membrane to the tissue or vital bone, and
- moving the membrane away from the tissue or vital bone for distraction at a speed of 0.5 to 2 mm per day,
- wherein the surface of the membrane facing the tissue or vital bone comprises osteoblasts attached to one or more compounds that biologically adhere to the osteoblasts, and is arranged so that the osteoblasts attach directly to the one or more compounds and not to the surface.
Dependencies are inferred from the claim text.