Back to results
US 7,731,973 B2Granted
Method of treating immune pathologies with low dose estrogen
AssigneesOregon Health & Science University, The United States of America as represented by the Department of Veterans Affairs
InventorHalina Offner
Life of this patent
Estimating the term…
Abstract
The invention provides a method of ameliorating a Th1-mediated immune pathology in a mammal. The method is practiced by administering a low dose of estrogen to the mammal. Optionally, an immunotherapeutic agent can also be administered to the mammal. Also provided are kits containing a low dose of estrogen and an immunotherapeutic agent.
Claims14
A method of ameliorating multiple sclerosis in a human subject, comprising
- selecting a human subject having multiple sclerosis;
- and
- administering a dose of estriol to the human subject sufficient to raise the serum concentration of estriol in the human subject to within the range from 30 pg/ml to 2,000 pg/ml,
- thereby ameliorating multiple sclerosis in said human subject.
1 more element
A method of ameliorating multiple sclerosis in a human subject, comprising
- selecting a human subject with multiple sclerosis;
- and
- administering estriol to the human subject in an amount sufficient to raise the serum concentration of estriol in said human subject to within the range from 10 pg/ml to 2,000 pg/ml and
- thereby ameliorating multiple sclerosis in said human subject.
1 more element
Dependencies are inferred from the claim text.