Biodegradable biocompatible implant

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, wherein said biodegradable membrane is a polymer film, a polymer textile, a polymer fleece, a layer of fused polymer particles or a combination thereof, thus forming at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, and having a thickness in a range between about 10 μm to about 3000 μm, wherein said at least one zone of impermeability to soft tissue and/or epithelial cells in-growth has a thickness in a range between about 50 μm to about 1000 μm.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, wherein said biodegradable membrane is made of fused polymer particles, wherein said fused polymer particles comprise microspheres, pellets or granules, having a size smaller than about 500 μm.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, wherein said membrane comprises at least two layers, one of said layers having a barrier function against soft tissue and/or epithelial cells in-growth in the scaffold, and a second layer, which is in direct contact with the surrounding living organism, allowing the stabilization and anchorage of soft tissue which tends to close the wound.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, said scaffold and/or said membrane including void spaces that are at least partially filled with at least one of air or gas, polymer, liquid, gel, or solid particles.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is comprised of an open porous scaffold and a membrane covering at least a part of said scaffold and being sealed to it such that said scaffold and said membrane form a single piece of matter that is resorbable by an organism, wherein at least a portion of the open porous scaffold allows an in-growth of regenerating bone tissue, further comprising at least one additive that is integrated into said scaffold and/or into said membrane, wherein said at least one additive comprises a plasticizer.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is made of a composite matrix and a membrane covering at least a part of said composite matrix and being sealed to it such that said composite matrix and said membrane form a single piece of matter, said composite matrix comprising a plurality of inorganic or synthetic granules bonded or held together by a synthetic polymer matrix, said inorganic or synthetic granules selected from the group consisting of solid granules, porous granules, hollow granules, hollow granules with at least one opening in the granule, and a mixture thereof;

• said granules having an equivalent-diameter in a range between about 100 μm to about 2000 μm.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is made of a composite matrix and a membrane covering at least a part of said composite matrix and being sealed to it such that said composite matrix and said membrane form a single piece of matter, said composite matrix comprising a plurality of inorganic or synthetic granules bonded or held together by a synthetic polymer matrix, said composite matrix including void spaces between adjacent granules that are at least partially filled with at least one of air or gas, polymer, liquid, gel, or solid particles.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is made of a composite matrix and a membrane covering at least a part of said composite matrix and being sealed to it such that said composite matrix and said membrane form a single piece of matter, said composite matrix comprising a plurality of inorganic or synthetic granules bonded or held together by a synthetic polymer matrix, said composite matrix including void spaces between adjacent granules that are filled with at least a biologically active substance.

Biocompatible implant for the treatment of defects in a living organism such as bone defects or tooth extraction wounds, comprising at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, wherein said implant is made of a composite matrix and a membrane covering at least a part of said composite matrix and being sealed to it such that said composite matrix and said membrane form a single piece of matter, said composite matrix comprising a plurality of inorganic or synthetic granules bonded or held together by a synthetic polymer matrix, wherein said biodegradable membrane is a polymer film, a polymer textile, a polymer fleece, a layer of fused polymer particles or a combination thereof, thus forming at least one zone of impermeability to soft tissue and/or epithelial cells in-growth, and having a thickness of about 10 μm to about 3000 μm.