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US 7,727,184 B2Granted
Biological revascularization
AssigneeMayo Foundation for Medical Education and Research
InventorsDavid R. Holmes, Jr., Robert S. Schwartz
Life of this patent
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Abstract
A catheter delivery system for delivering a treatment substance to an occlusion in a lumen of a tubular vessel includes a tubular catheter and a treatment substance. The tubular catheter includes a central lumen passing between a proximal end and a distal end adjacent to an inflatable balloon. The treatment substance is in a form that is configured to be deliverable through the central lumen of the catheter into the lumen of the tubular vessel and to solidify in the vessel.
Claims9
A method of delivering a treatment substance to a chronic total occlusion, the method comprising:
- (a) providing a tubular catheter having a lumen passing between a proximal end and a distal end;
- (b) providing a treatment substance comprising an angiogenesis agent or an occlusion dissolving agent for delivery through the tubular catheter to a position adjacent the occlusion;
- (c) inserting the tubular catheter into a mammalian vasculature;
- (d) advancing the tubular catheter through the vasculature until the distal end of the tubular catheter is adjacent to the chronic total occlusion;
- and
- (e) injecting the treatment substance through the tubular catheter to the position adjacent the chronic total occlusion.
3 more elements
Dependencies are inferred from the claim text.