PRRSV subunit vaccines
AssigneeBoehringer Ingelheim Vetmedica GmbH
InventorsEric M. Vaughn, Richard Stammer
Life of this patent
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Abstract
Vaccines effective against PRRSV include at least one portion of PRRSV ORF1. Such vaccines, upon administration, provoke an immune response in PRRSV-susceptible animals. Moreover, compositions in accordance with the present invention provide immune response up to and including protective immunity against PRRSV as well as reduce the severity of PRRSV and/or incidence of PRRSV. Selected portions of ORF1 can be used singularly, in combination with one another, in combination with other PRRSV ORFs, and in combination with other PRRSV vaccines.
Claims14
An immunogenic composition capable of inducing an immune response against PRRSV comprising:
- a vector comprising first portion of PRRSV ORF1 DNA, said first portion having at least 21 contiguous nucleotides from said PRRSV ORF1 DNA nucleotide base pair of any of sequences selected from the group consisting of any one of SEQ ID Nos. 1-14;
- and a suitable pharmacological carrier.
Dependencies are inferred from the claim text.