US 7,712,198 B2 · Microneedle array device and its fabrication method

Abstract

A microneedle array device and its fabrication method are provided. The microneedle array device comprises a supporting pad and a plurality of microneedles. Each microneedle has a top portion with a via thereon, thereby the microfluid may flow in or out. The intersection between the top portion and the inner tube of a microneedle forms a convex needle structure, and is almost perpendicular to the upper surface. For each microneedle, a hollow closed tube is formed between the top portion and the supporting pad. The fabrication method uses substrates with high transmittance and a plurality of convex area thereon as upper and lower caps, and applies a photolithography process to fabricate a microneedle array mold. It then sputters or electroplates metal material on the mold. The microneedle array is formed after having taken off the mold.

Claims17

Dependent claims

A method of fabricating a microneedle array device, comprising the steps of:

(1) providing a substrate, and forming a plurality of concave areas on a surface of said substrate;
(2) coating a layer of photo-sensitive material on top of said substrate, and coating a layer of light transmission material on top of said photo-sensitive material;
(3) using a patterned mask for exposure and development of said photo-sensitive material on said light transmission material to obtain a polymer hollow microneedle array mold using said light transmission material as a base;
and
(4) forming a microneedle array device using said polymer hollow microneedle array mold.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

11/754,368Filed 29 May 2007 · division

Priority

TW 93121337 A16 Jul 2004

Published

US 2007/0233016 A14 Oct 2007

Granted

11 May 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification14 codes

B81C 1/00111
Without movable or flexible elements: tips, pillars, i.e. raised structures
A61B 17/205
For vaccinating or cleaning the skin previous to the vaccination: vaccinating by means of needles or other puncturing devices
A61M 37/0015
Other apparatus for introducing media into the body ; Percutany, i.e. introducing medicines into the body by diffusion through the skin: by using…
A61M 2037/0053
By using microneedles: methods for producing microneedles

Microneedle array device and its fabrication method

Life of this patent

Microneedle array device and its fabrication method

Life of this patent

Abstract

Claims17