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US 7,709,215 B2Granted
Method for diagnosing and treating acute joint injury
AssigneeCytonics Corporation
InventorGaetano J. Scuderi
Life of this patent
Estimating the term…
Abstract
The present invention provides methods, reagents and kits for diagnosing and/or for the prognosis of non-autoimmune acute joint inflammation by detecting cytokine biomarkers in a sample obtained from an individual thought to be suffering from joint injury. The cytokine biomarkers used with the methods and kits of the present invention are IL-6, MIP-1β, MCP1 and IFNγ.
Claims8
A method of selecting a patient for treatment, wherein the patient has non-autoimmune acute pain of a joint, the method comprising:
- detecting the level of IL-6 and at least one other cytokine selected from the group consisting of MCP-1, MIP-1β and IFNγ relative to levels in synovial fluid from a joint in a normal individual, wherein a detectable level of IL-6 greater than 0.07 pg/ml and the at least one other cytokine is indicative of a patient to be selected for treatment.
Dependencies are inferred from the claim text.