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US 7,705,033 B2Granted
Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof
AssigneeBristol-Myers Squibb Company
InventorsTruc Chi Vu, David B. Brzozowski, Rita Fox, Jollie Duaine Godfrey, Jr., Ronald L. Hanson, Sergei V. Kolotuchin, John A. Mazzullo, Ramesh N. Patel, Jianji Wang, Kwok Wong, Jurong Yu, Jason J. Zhu, David R. Magnin, David J. Augeri, Lawrence G. Hamann
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Abstract
Methods and compounds for production of cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV are provided.
Claims1
A method for preparing compound M″
- which comprises treating compound M′
- with about 1 to about 3.5 equivalents of water at room temperature to provide compound M″.
Dependencies are inferred from the claim text.