Fluorogenic dyes
AssigneeNovartis Vaccines and Diagnostics, Inc.
InventorsDaniel J. Suich, Ronald N. Zuckermann
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Abstract
Fluorogenic or chromogenic dyes are useful as reporter molecules for detecting cell entry by a specific molecule.
Claims6
A library of compounds that is to be screened for their ability to be internalized by a desired cell, the library comprising a plurality of different compounds, wherein the different compounds in such library are covalently attached to a fluorogenic reporter molecule that becomes fluorescent after it is internalized by a cell, and wherein the reporter molecule is selected from the group consisting of:
A fluorogenic compound having a structure selected from the group consisting of:
Dependencies are inferred from the claim text.