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US 7,691,596 B2Granted
Methods for determining GTP cyclohydrolase I or II activity
AssigneeBASF SE
InventorsAnnette Freund, Franz Röhl, Henning Althöfer, Marvin Karos, Bruno Kaesler, Thierry Lacour
Life of this patent
Estimating the term…
Abstract
The present invention relates to methods for determining GTP Cyclohydrolase I or II activity in a sample.
Claims3
A method for determination of GTP cyclohydrolase I or II activity comprising the steps of:
- a) adding GTP or GTP analog, NAD+ and formate dehydrogenase to a sample comprising GTP cyclohydrolase II or I;
- b) determining the production of NADH of the sample, and
- c) correlating the production of NADH with GTP I or II activity, wherein the production of NADH is indicative of GTP cyclohydrolase I or II activity.
Dependencies are inferred from the claim text.