Lead with fibrous matrix coating and methods related thereto

A lead system comprising:

• one or more leads, each lead comprising:
• a lead body extending from a lead proximal end portion to a lead distal end portion, and having an intermediate portion therebetween;
• one or more tissue sensing/stimulation electrodes disposed along the lead body;
• one or more terminal connections disposed along the lead proximal end portion;
• one or more conductors contained within the lead body extending between the tissue sensing/stimulation electrodes and the terminal connections;
• a fibrous matrix coating substantially mimicking structure of tissue, disposed onto at least a portion of the lead body and/or sensing/stimulation electrodes;
• wherein the fibrous matrix coating comprises fibers with diameters of about 10 nm to about 3000 nm and a basis weight of about 0.01 g/m2 to about 500 g/m2;
• a connector assembly, coupled to the one or more terminal connections;
• and
• an implantable medical device, coupled to the connector assembly of the one or more leads.

A method of manufacturing a lead, the method comprising:

• forming a lead;
• and
• disposing a fibrous matrix coating that substantially mimics structure of tissue, on all or a portion of the lead;
• wherein the fibrous matrix coating comprises fibers with diameters of about 10 nm to about 3000 nm and a basis weight of about 0.01 g/m2 to about 500 g/m2.