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US 7,689,277 B2Granted
Neural stimulation for treatment of metabolic syndrome and type 2 diabetes
AssigneeLeptos Biomedical, Inc.
InventorJohn D. Dobak, III
Life of this patent
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Abstract
Systems and methods are described for treating metabolic syndrome and/or Type 2 diabetes, and/or one or more of their attendant conditions, by neural stimulation. In one embodiment, an implantable pulse generator is electrically coupled to a peripheral nerve, such as the splanchnic nerve. Neural stimulation configured to either block transmission or stimulate transmission of the peripheral nerve may be used to treat metabolic syndrome and Type 2 diabetes.
Claims12
A method, of treating at least dyslipidemia comprising:
- selecting a patient suffering from dyslipidemia;
- electrically modulating a splanchnic nerve of the patient in a stimulation pattern that ameliorates or eliminates dyslipidemia;
- wherein said stimulation pattern comprises a stimulation intensity, and said stimulation intensity is between 0.005 and 5.0 mA-msec;
- wherein said stimulation pattern comprises an on time and an off time;
- and wherein said off time is no less than said on time;
- wherein said stimulation pattern comprises a frequency, a pulse width, and a current;
- and
- wherein said frequency is between 0.1 Hz and 50 Hz;
- said pulse width is between 100 microseconds and 1 millisecond;
- and said current is between 0.1 mA and 10 mA.
7 more elements
Dependencies are inferred from the claim text.