Automatic detection of critical dermoscopy features for malignant melanoma diagnosis
AssigneesStoecker & Associates, a Subsidiary of The Dermatology Center, LLC, The Curators of the University of Missouri
InventorsWilliam V. Stoecker, Randy H. Moss, R. Joe Stanley, Xiaohe Chen, Kapil Gupta, Bijaya Shrestha, Pavani Jella
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Abstract
Improved methods for computer-aided analysis of identifying features of skin lesions from digital images of the lesions are provided. Improved preprocessing of the image that 1) eliminates artifacts that occlude or distort skin lesion features and 2) identifies groups of pixels within the skin lesion that represent features and/or facilitate the quantification of features are provided including improved digital hair removal algorithms. Improved methods for analyzing lesion features are also provided.
Claims22
A method for automatically identifying a border between a skin lesion and surrounding skin on a digital image of a skin lesion comprising:
- a. preprocessing the image to identify pixels that represent features other than skin and lesion;
- b. identifying a bounding box in the shape of a rectangle having four sides by bounding box methods wherein the box borders are determined by a maxima of subtraction curves applied to horizontal and vertical projections of numbers representing a single-plane image of the lesion to determine a first lesion ratio estimate of the image;
- and wherein the absence of a bounding box side indicates that the lesion may extend to the periphery of the image, and the presence of a bounding box indicates that the lesion does not extend to the periphery of the image;
- c. if one or more bounding box sides are not found, determining a first estimate of the lesion ratio, which is the ratio of the area of the lesion to the area of the entire image, using a mean lesion ratio estimate wherein the mean lesion ratio estimate is applied to provide approximate location(s) of any missing bounding box sides;
- d. subsequently applying a lesion ratio offset, which is a correction factor, to the lesion ratio estimate to produce a corrected lesion ratio estimate, said lesion ratio offset being determined by running an automatic, self-training classifier algorithm that incorporates color and histogram data from the area defined by the bounding box sides identified in step b or c and/or by an area identified by inputting the lesion ratio estimate into a segmentation algorithm for identifying a border between a skin lesion and the surrounding skin;
- and
- e. inputting said corrected lesion ratio estimate into a segmentation algorithm for identifying a border between a skin lesion and surrounding skin;
- whereby said border is determined automatically.
Dependencies are inferred from the claim text.