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US 7,687,053 B2Granted
Embolic compositions with non-cyanoacrylate rheology modifying agents
AssigneeBoston Scientific Scimed, Inc.
InventorStephen C. Porter
Life of this patent
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Abstract
Compositions for embolization are disclosed herein. The compositions disclosed can have a matrix-forming component, a solid-aggregate material, and a rheology modifying agent, wherein the matrix-forming component includes at least alkyl cyanoacrylate monomers, a stabilizer, and a plasticizer, and the solid-aggregate material includes at least a radiopacifier. The composition and a method of administering the composition are useful for treating vasculature abnormalities, particularly when the composition solidifies upon contact with an ionic environment, such as blood.
Claims24
A medical composition comprising:
- a matrix-forming component comprising alkyl cyanoacrylate monomers, a stabilizer, and a plasticizer;
- a solid aggregate material comprising a radiopacifier;
- and
- a polymeric non-cyanoacrylate rheology modifying agent that has an average molecular weight greater than 200,000, wherein the non-cyanoacrylate rheology modifying agent is a polymeric compound selected from the group consisting of poly(acrylates), poly(alkenes), poly(alkyl oxides), poly(amides), poly(carbonates), cellulosic polymers and copolymers, poly(dienes), poly(esters), poly(methacrylates), poly(saccharides), poly(siloxanes), poly(styrenes), poly(urethanes), poly(vinyl ethers), iodinated polymers and copolymers thereof, and mixtures thereof.
1 more element
Dependencies are inferred from the claim text.