Sensing apparatus and method
AssigneeDNA Electronics Limited
InventorsChristofer Toumazou, Sunil Purushothaman
Life of this patent
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Abstract
A sensing apparatus comprising an ion sensitive field effect transistor arranged to generate an electrical output signal in response to localized fluctuations of ionic charge at or adjacent the surface of the transistor, and means for detecting the electrical output signal from the ion sensitive field effect transistor, the localized fluctuations of ionic charge indicating events occurring during a chemical reaction.
Claims15
A sensing apparatus comprising two ion sensitive field effect transistors, which are arranged to generate an electrical output signal in response to a chemical reaction to which the transistors are exposed and means for discriminating discrete fluctuation in the electrical output signal, the discrete fluctuations indicating reaction intermediaries occurring during the chemical reaction, a first of the transistors being provided with an enzyme linked layer and a second of the transistors being provided with a non-enzyme linked layer;
- and said apparatus further comprising means for determining the difference between the electrical signals generated by said first and second transistors to provide said electrical output signal.
Dependencies are inferred from the claim text.