Tenascin-W compositions and uses thereof
AssigneeNovartis Forschungsstiftung Zweignlederlassung Friedrich Miescher Institute for Biomedical Research
InventorsRuth Chiquet-Ehrismann, Arnaud Scherberich
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Abstract
Tenascin-W, an extracellular matrix molecule that is specifically expressed in metastatic tumours is provided. A system comprising a sample expressing tenascin-W is used as an in vitro method for screening possible anti-tumour agents or for agents that promote osteogenesis.
Claims7
An isolated antibody that specifically recognizes amino acids 791-1054 of the polypeptide having the amino acid sequence shown in SEQ ID NO:
- 4.
An isolated antibody that specifically recognizes one or more of the three C-terminal fibronectin III repeats of mammalian tenascin W.
Dependencies are inferred from the claim text.