Selective binding materials
AssigneeCranfield University
InventorsSergiy Anatoliyovich Piletsky, Olena Volodimirivna Piletska, Khalku Karim, Anthony Peter Francis Turner, Alessandra Bossi
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Abstract
A template (a molecule preferably of molecular size >500 Da, or a larger entity such as a cell, virus or tissue sample) is dissolved or suspended in a fluid. The fluid is frozen, and the template is removed (e.g. by dissolution or electrophoresis, or mechanically) to leave an “imprinted” frozen fluid. This is capable of selectively adsorbing the template substance. It is usable as a separation medium, a recognition element in sensors and assays, and as a catalyst.
Claims9
A process for forming a selective binding material comprising:
- (a) preparing a composition by suspending or dissolving a template material into a carrier wherein said carrier is in a liquid state;
- (b) freezing the composition to convert said carrier from a liquid state to a solid state and forming a solid composition;
- and
- (c) at least partially removing the template material from the solid composition to leave solid carrier with binding sites at locations where the template material has been removed, to form a selective binding material, wherein
- the carrier is selected from the group consisting of water, aqueous solvents, inorganic liquids, organic solvents, metals, fusible inorganic compounds, and gases.
Dependencies are inferred from the claim text.