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US 7,682,808 B2Granted
Coagulation and fibrinolytic cascades modulator
AssigneeThe Board of Trustees of the University of Illinois
InventorsJames H. Morrissey, Stephanie A. Smith, Roberto Docampo, Nicola J. Mutch
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Abstract
A thromboplastin reagent comprises (i) TF, (ii) a phospholipid, and (iii) a polyP TFPI blocker.
Claims14
A thromboplastin reagent, comprising:
- (i) tissue factor (TF),
- (ii) a phospholipid, and
- (iii) an inorganic polyphosphate tissue factor pathway inhibitor (polyP TFPI) blocker.
A reagent for a clotting assay, comprising:
- an activator of clotting, and
- polyP.
Dependencies are inferred from the claim text.