US 7,682,804 B2Granted

Diagnostics and therapeutics for macular degeneration-related disorders

AssigneeUniversity of Iowa Research Foundation

InventorsGregory S. Hageman, Robert F. Mullins

Life of this patent

Estimating the term…

Abstract

The invention relates to methods for diagnosing and treating macular degeneration-related disorders. The invention also related to methods for identifying genes that cause macular degeneration-related disorders.

Claims4

Dependent claims

A method for diagnosing, or identifying a predisposition to the development of, age-related macular degeneration in a subject, comprising detecting in a biological sample from the subject the presence or abnormal levels of an autoantibody against, or an immune complex containing, at least one macular degeneration-associated molecule, wherein the macular degeneration-associated molecule is C3 convertase.

Dependencies are inferred from the claim text.

Facts

Application: 12/026,420Filed 5 Feb 2008 · continuation
Priority: 22 Feb 2000
Published: US 2008/0131418 A15 Jun 2008
Granted: 23 Mar 2010
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C12Q 1/6883
Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes: for diseases caused by alterations of genetic material
A61P 37/00
Drugs for immunological or allergic disorders
G01N 33/564
Immunoassay; Biospecific binding assay; Materials therefor: for pre-existing immune complex or autoimmune disease , i.e. systemic lupus…
G01N 33/6893
Involving proteins, peptides or amino acids: related to diseases not provided for elsewhere

Family

Application09/510,230Parent of this continuation-in-part · filed 22 Feb 2000
Application60/200,698Us provisional application · filed 29 Apr 2000
Application09/845,745Parent of this continuation-in-part · filed 30 Apr 2001
Application10/084,639Parent of this continuation · filed 25 Feb 2002
Application11/205,370Parent of this continuation · filed 16 Aug 2005
US 2008/0131418 A1Pre-grant publication · published 5 Jun 2008
US 7,344,846 B2Parent of this continuation
US 7,011,952 B2Parent of this continuation
Application10/084,639Parent of this continuation-in-part
US 2002/0015957 A1Published application
US 2003/0017501 A1Published application
US 2005/0287601 A1Published application
US 7,682,804 B2This patent

From the US filing history. Foreign family members aren’t listed.

Timeline

Citations

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Abstract

Facts

Application

12/026,420Filed 5 Feb 2008 · continuation

Priority

22 Feb 2000

Published

US 2008/0131418 A15 Jun 2008

Granted

23 Mar 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

C12Q 1/6883
Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes: for diseases caused by alterations of genetic material
A61P 37/00
Drugs for immunological or allergic disorders
G01N 33/564
Immunoassay; Biospecific binding assay; Materials therefor: for pre-existing immune complex or autoimmune disease , i.e. systemic lupus…
G01N 33/6893
Involving proteins, peptides or amino acids: related to diseases not provided for elsewhere

Family

Application09/510,230Parent of this continuation-in-part · filed 22 Feb 2000

Application60/200,698Us provisional application · filed 29 Apr 2000

Application09/845,745Parent of this continuation-in-part · filed 30 Apr 2001

Application10/084,639Parent of this continuation · filed 25 Feb 2002

Application11/205,370Parent of this continuation · filed 16 Aug 2005

US 2008/0131418 A1Pre-grant publication · published 5 Jun 2008

US 7,344,846 B2Parent of this continuation

US 7,011,952 B2Parent of this continuation

Application10/084,639Parent of this continuation-in-part

US 2002/0015957 A1Published application

US 2003/0017501 A1Published application

US 2005/0287601 A1Published application

US 7,682,804 B2This patent

From the US filing history. Foreign family members aren’t listed.