Immunomodulation using placental stem cells
AssigneeAnthrogenesis Corporation
InventorsCasper Paludan, James Edinger, Ryhor Harbacheuski, RoseAnn Murray, Robert J. Hariri
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Abstract
The present invention provides methods of immunomodulation using placental stem cells and placental stem cell populations. The invention also provides methods of producing and selecting placental cells and cell populations on the basis of immunomodulation, and compositions comprising such cells and cell populations.
Claims13
A method of suppressing an immune response comprising contacting a plurality of T cells or natural killer (NK) cells with 1 million to 10 billion placental stem cells for a time sufficient for said placental stem cells to detectably suppress an immune response, wherein said placental stem cells detectably suppress T cell proliferation stimulated by Epstein-Barr virus antigen-presenting B cells;
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- wherein at least 80% of said 1 million to 10 billion said placental stem cells express CD200.
Dependencies are inferred from the claim text.