Medical article and method of making and using the same

A medical article, comprising:

• a plastic portion;
• and
• a blocked color changing specie;
• wherein the blocked color changing specie is capable of being active after post-processing, and wherein the post-processing is different than manufacturing processes employed to make the medical article;
• and
• wherein the active color changing specie is capable of changing color after exposure to a color change activator;
• and
• wherein the active color changing specie comprises a dye having a formula selected from the group consisting of Formula IV and Formula V:
• wherein A is selected from the group consisting of C—R22, NH, O, S+, and N—R21;
• wherein B is selected from the group consisting of C—R22, NH, O, S, and N—R22;
• and
• wherein R17-R22 are, individually, selected from the group consisting of H, alkyl, aryl, acyl, halogen, thiocarbamate, enamine, imine, acetal, sulfenyl, sulfonyl, phosphoryl, imide, and combinations comprising at least one of the foregoing.

A medical article, comprising:

• a plastic portion;
• and
• a blocked color changing specie;
• wherein the blocked color changing specie is capable of being active after sterilization;
• wherein the active color changing specie is capable of changing color after exposure to a color change activator.