Floating pharmaceutical composition comprising an active phase and a non-active phase

A tablet floating pharmaceutical composition comprising:

• a) a first phase, termed active phase, consisting of a composition comprising at least one active ingredient and a disintegrating agent comprising highly substituted hydroxypropylcellulose that is at least 50% substituted, provided in an amount of less than 15% by weight of the active phase and in a form to obtain a disintegrating effect while preventing the formation of a continuous network;
• b) a second phase, termed inactive phase, comprising at least one gas-generating system and at least one hydrophilic polymer or a porous mineral compound, the active phase comprising a quantity of active ingredient(s) constituting at least 80% by weight of the active phase.