Method and devices for dry loading of chromatography resins

A chromatography column comprising:

• an enclosure, a first port and a second port,
• said first port being provided with an inlet valve,
• said enclosure being in communication with a tank via said inlet valve and with a pump via said second port, said tank comprising a dry chromatography resin made of particles having a size distributed between a minimum size and a maximum size,
• wherein said inlet valve comprises a chamber, an inlet duct and a piston,
• the chamber communicating with the enclosure through a first aperture,
• the inlet duct communicating with the chamber through a second aperture and being connected to the tank, and
• the piston being movable in the chamber between a closing position, where it closes the first and second apertures, and an opening position, where it opens the first and second apertures and it lets free substantially all the space of the chamber between the first and second apertures.