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US 7,678,910 B2Granted
Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]Pyridine-2-carboxylic acid
AssigneeDaiichi Sankyo Company, Limited
InventorsHiroshi Nagasawa, Koji Sato, Tsutomu Yagi, Yasuo Kitani
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Abstract
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, [F14] is prepared by reacting a compound of formula (6) or a salt thereof, with a trihalogenoacetyl halide in the presence of a base, followed by hydrolysis.
Claims5
A process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid of formula (5) or a salt thereof, comprising:
- reacting a compound of formula (6) or a salt thereof,
- with a trihalogenoacetyl halide in the presence of a base to obtain a reaction product mixture, and
- hydrolyzing the reaction product mixture.
Dependencies are inferred from the claim text.