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US 7,678,888 B2Granted
Stable oxidation resistant powdered hemoglobin, methods of preparing same, and uses thereof
AssigneeAlbert Einstein College of Medicine of Yeshiva University
InventorsJoel M. Friedman, Mahantesh S. Navati
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Abstract
The present invention provides oxygenated hemoglobins in powdered form and methods of preparing a powdered form of a protein, such as hemoglobin, which comprise (a) mixing a solution of the protein with inulin, and optimally with a reducing sugar such as glucose or tagatose, and (b) drying the mixture. Also provided are blood substitutes formed from reconstituted powdered hemoglobins, and methods of treatment using the blood substitutes.
Claims16
A method of preparing a powdered form of a protein, which comprises:
- (a) mixing a solution of the protein with inulin and tagatose, and
- (b) drying the mixture.
Dependencies are inferred from the claim text.