Substituted 4-aminocyclohexanol compounds

A substituted 4-aminocyclohexanol compound corresponding to formula I,

• wherein
• R1 and R2 independently of one another represent H;
• C1-8-alkyl or C3-8-cycloalkyl, in each case saturated or unsaturated, branched or unbranched, mono- or polysubstituted or unsubstituted;
• aryl- or heteroaryl, in each case mono- or polysubstituted or unsubstituted;
• or aryl, C3-8-cycloalkyl or heteroaryl bonded via C1-3-alkylene and in each case mono- or polysubstituted or unsubstituted;
• wherein R1 and R2 are not both H, or the radicals R1 and R2 together form a ring and represent CH2CH2OCH2CH2, CH2CH2NR5CH2CH2 or (CH2)3-6,
• wherein
• R5 represents H;
• C1-8-alkyl or C3-8-cycloalkyl, in each case saturated or unsaturated, branched or unbranched, mono- or polysubstituted or unsubstituted;
• aryl- or heteroaryl, in each case mono- or polysubstituted or unsubstituted;
• or aryl, C3-8-cycloalkyl or heteroaryl bonded via C1-3-alkylene and in each case mono- or polysubstituted or unsubstituted;
• R3 represents C1-8-alkyl or C3-8-cycloalkyl, in each case saturated or unsaturated, branched or unbranched, mono- or polysubstituted or unsubstituted;
• or aryl, C3-8-cycloalkyl or heteroaryl bonded via a saturated or unsaturated, branched or unbranched, substituted or unsubstituted C1-4-alkyl group and in each case unsubstituted or mono- or polysubstituted;
• R4 represents C3-8-cycloalkyl, aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted;
• —CHR6R7, —CHR6—CH2R7, —CHR6—CH2—CH2R7, —CHR6—CH2—CH2—CH2R7, —C(Y)R7, —C(Y)—CH2R7, —C(Y)—CH2—CH2R7 or —C(Y)—CH2—CH2—CH2R7;
• or —R8-L-R9
• wherein
• Y=O, S or H2;
• R6 represents H;
• C1-7-alkyl, saturated or unsaturated, branched or unbranched, mono- or polysubstituted or unsubstituted;
• or C(O)O—C1-6-alkyl, saturated or unsaturated, branched or unbranched, mono- or polysubstituted or unsubstituted;
• R7 represents H;
• C3-8-cycloalkyl, aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted;
• R8 represents aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted;
• L represents —C(O)—NH—, —NH—C(O)—, —C(O)—O—, —O—C(O)—, —O—, —S— or —S(O)2—;
• and
• R9 represents aryl or heteroaryl, in each case unsubstituted or mono- or polysubstituted,
• or a salt thereof with a physiologically tolerated acid.