Compounds for alzheimer's disease

A compound of Formula II, a pharmaceutically acceptable salt thereof, or a pharmaceutical composition having such a compound,

• Wherein one of R2 and R4 is —COOH, while the other is —H;
• R1, R3, and R5, independent of one another, are chosen from hydro, hydroxyl, halo, alkyl, alkoxy, haloalkyl, haloalkoxy, —N(C1-3 alkyl)2, —NH(C1-3 alkyl), —C(═O)NH2, —C(═O)NH(C1-3 alkyl), —C(═O)N(C1-3 alkyl)2, —S(═O)2(C1-3 alkyl), —S(═O)2NH2, —S(═O)2N(C1-3 alkyl)2, —S(═O)2NH(C1-3 alkyl), —CHF2, —OCF3, —OCHF2, —SCF3, —CF3, —CN, —NH2, and —NO2;
• R6 is hydro;
• one of R7, R8 or R9 is haloalkyl, while the other two are, independent of one another, chosen from hydro, hydroxyl, halo, alkyl, alkoxy, haloalkyl, haloalkoxy, —N(C1-3 alkyl)2, —NH(C1-3 alkyl), —C(═O)NH2, —C(═O)NH(C1-3 alkyl), —C(═O)N(C1-3 alkyl)2, —S(═O)2(C1-3 alkyl), —S(═O)2NH2, —S(═O)2N(C1-3 alkyl)2, —S(═O)2NH(C1-3 alkyl), —CHF2, —OCF3, —OCHF2, —SCF3, —CF3, —CN, —NH2, —NO2, —C(═O)—N-morpholino, -cyclohexyl, -morpholino, -pyrrolidinyl, -piperazinyl, —(N-methyl)-piperazinyl, —OCH2-phenyl, -pyridinyl, methylenedioxy, ethylenedioxy, —C(═O)OCH2CH3 substituted furanyl, para-(C(═O)OCH2CH3)-phenyl, and —O—Si(CH3)2(C(CH3)3);
• or optionally two adjacent of R6-R9 can be taken together to form a 4-7 member optionally substituted aryl or cycloalkyl ring;
• R10 is hydro;
• and
• R11 is an optionally substituted phenyl or heterocyclic group.