Induction of immune tolerance
AssigneeGenzyme Corporation
InventorJohn M. Williams
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Abstract
Methods of inducing immune tolerance by administering an immunosuppressive agent and a compound represented by Formula (I) are disclosed: Additionally methods of suppressing an immune response by administering an immunosuppressive agent and a compound represented by Formula (I) are disclosed. Further disclosed are methods for treating autoimmune diseases by administering an immunosuppressive agent and a compound represented by Formula (I). The variables of Formula (I) are described herein.
Claims2
A method of inhibiting rejection of a transplanted organ, tissue or cell in a recipient mammal, the method comprising the step of administering to the recipient mammal an effective amount of an anti-lymphocyte antibody and an effective amount of a compound represented by the following structural formula:
- or a physiologically acceptable salt of the compound.
Dependencies are inferred from the claim text.