Back to results
US 7,678,779 B2Granted
Methods for the administration of amifostine and related compounds
AssigneeMedImmune, LLC
InventorsDavid Cassatt, Christine A. Fazenbaker
Life of this patent
Estimating the term…
Abstract
The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy or chemotherapy in a manner that significantly reduces or decreases the adverse or undesirable side-effects of the compounds as compared with conventional intravenous administration.
Claims30
A method of protecting against xerostomia or mucositis caused by radiation therapy comprising:
- subcutaneously administering to a subject in need thereof an effective amount of amifostine about 8 to about 12 hours before the subject is exposed to the radiation therapy.
A method of protecting against xerostomia or mucositis caused by cancer chemotherapy comprising:
- subcutaneously administering to a subject in need thereof an effective amount of amifostine about 8 to about 12 hours before the subject is exposed to the chemotherapy.
Dependencies are inferred from the claim text.