ILK inhibitors for the treatment of renal disease
AssigneeQLT Inc.
InventorsMatthias Kretzler, Patricia Logan
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Abstract
The invention relates to the treatment of renal diseases using modulators of integrin linked kinase. Methods of treatment as well as therapeutic agents including antisense, small molecules, catalytic peptides and antibodies are disclosed. The agents of the invention may also be used in combination with traditional therapies for renal disease including ACE inhibitors. An advantage of the invention is that it treats one of the causes of renal disease, rather than just ameliorating symptoms, and can help prevent the progression of renal disease to the point of acute renal failure.
Claims24
A method for treating a patient with renal dysfunction, the method comprising:
- administering an effective dose of an integrin linked kinase (ILK) inhibitor to said patient.
A method for lowering protein levels in urine, the method comprising:
- administering an effective dose of an integrin linked kinase (ILK inhibitor to a patient with renal dysfunction.
Dependencies are inferred from the claim text.