Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
AssigneeKitakyushu Foundation for the Advancement of Industry, Science and Technology
InventorHiroharu Kawahara
Life of this patent
Estimating the term…
Abstract
A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg per 1,000,000 cells; with the novel human cell strain being further characterized in that after a gene encoding a desired protein is transfected into it, the transfected cell is subsequently cultured.
Claims3
A human cell strain SC-02MFP deposited as Accession Number FERM BP-10078.
A human cell strain SC-01MFP deposited as Accession Number FERM BP-10077.
A human cell strain capable of continuous production of a protein from an exogenous gene at a yield of 1 ng to 10 μg/day per 1,000,000 cells at least over a 2-month period, wherein said human cell strain is SC-01MFP (Accession No. FERM BP-10077) or SC-02MFP (Accession No. FERM BP-10078).
Dependencies are inferred from the claim text.