Cloned genome of infectious hepatitis C virus strain HC-TN and uses thereof
AssigneeThe United States of America as represented by the Department of Health and Human Services
InventorsJens Bukh, Robert H. Purcell, Suzanne U. Emerson, Akito Sakai
Life of this patent
Estimating the term…
Abstract
Embodiments described herein include nucleic acid sequences, which encode hepatitis C virus of strain HC-TN, genotype 1a, proteins and polypeptides and fragments thereof. Use of these compositions, and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV are also contemplated.
Claims7
A purified or isolated nucleic acid molecule comprising a hepatitis C virus (HCV) 5′ untranslated region (UTR), a sequence that encodes SEQ. ID. NO.:
- 2, and a HCV 3 ′UTR, wherein said nucleic acid produces a HCV that infects chimpanzees.
A purified or isolated nucleic acid molecule comprising a sequence that encodes SEQ. ID. NO.:
- 2.
Dependencies are inferred from the claim text.