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US 7,678,567 B2Granted
Optical biosensor
AssigneeKabushiki Kaisha Toshiba
InventorsIkuo Uematsu, Ichiro Tono, Kayoko Oomiya, Hideo Eto
Life of this patent
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Abstract
An optical biosensor has a total reflection plate so as to totally internally reflect and transmit an incident light, a first grating and a second grating disposed separately on the total reflection plate, and a sensing membrane that is containing an enzyme and a chromogenic reagent and is sandwiched by the first and second gratings on the total reflection plate.
Claims13
An optical biosensor comprising:
- a light source;
- a first grating diffracting an incident light emitted from the light source;
- a total reflection plate interposed between the light source and the first grating, including a glass layer and a silicone oxide layer provided on a surface of the glass layer, so as to totally internally reflect and transmit a diffracted light diffracted by the first grating;
- a second grating diffracting a transmitted light transmitted within the total reflection plate and outputting a diffracted light diffracted by the second grating to the outside of the total reflection plate;
- a light receiving element receiving the diffracted light diffracted by the second grating;
- and
- a sensing membrane in contact with the silicon oxide layer, that includes an enzyme and a chromogenic reagent and is provided between the first grating and the second grating on the total reflection plate, wherein
- the first grating and the second grating are in contact with the silicon oxide layer of the total reflection plate, and the diffracted light diffracted by the first grating is internally reflected between a bottom of the glass layer and a top surface of the silicon oxide layer.
5 more elements
An optical biosensor comprising:
- a light source;
- a first grating diffracting an incident light emitted from the light source;
- a total reflection plate interposed between the light source and the first grating including a glass layer and a titanium oxide layer provided on a surface of the glass layer, so as to totally internally reflect and transmit a diffracted light diffracted by the first grating;
- a second grating diffracting a transmitted light transmitted within the total reflection plate and outputting a diffracted light diffracted by the second grating to outside of the total reflection plate;
- a light receiving element receiving the diffracted light diffracted by the second grating;
- and
- a sensing membrane in contact with the titanium oxide layer, including an enzyme and a chromogenic reagent and being provided between the first grating and the second grating on the total reflection plate, wherein
- the first grating and the second grating are in contact with the titanium oxide layer of the total reflection plate, and the diffracted light diffracted by the first grating is internally reflected between a bottom of the glass layer and a top surface of the titanium oxide layer.
5 more elements
Dependencies are inferred from the claim text.