Method and apparatus for controlling air pressure in an organ or tissue container
AssigneeOrgan Recovery Systems, Inc.
InventorsDavid Walter Wright, Douglas Schein, John Brassil
Life of this patent
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Abstract
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The apparatus and methods include the organ cassette with one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue within the cassette, and including a pressure control device to allow pressure inside the portable housing to be varied.
Claims44
An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising:
- a portable housing, the portable housing including more than one lid that forms a substantially airtight seal with the portable housing;
- and
- an organ or tissue supporting surface configured to support the organ or tissue within the portable housing while allowing effluent medical fluid to pass through the organ or tissue,
- wherein the portable housing is configured to be received by at least one of a perfusion device, a transporter and a diagnostic device,
- wherein the portable housing includes one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue, and
- wherein each of the lids includes a pressure control valve that allows pressure inside the portable housing to be varied, the pressure control valve being configured to restrict the rate at which external pressure changes are transmitted to the inside of the portable housing.
An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising:
- a portable housing, the portable housing including more than one lid that forms a substantially airtight seal with the portable housing;
- and
- an organ or tissue supporting surface configured to support the organ or tissue within the portable housing while allowing effluent medical fluid to pass through the organ or tissue,
- wherein the portable housing is configured to be received by at least one of a perfusion device, a transporter and a diagnostic device,
- wherein the portable housing includes one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue,
- wherein the portable housing includes a closable vent that allows pressure inside the portable housing to be varied, and a pressure control valve that allows the pressure inside the portable housing to be varied, and is configured to restrict the rate at which external pressure changes are transmitted to the inside of the portable housing and to maintain the pressure inside the portable housing at a desired pressure, and
- wherein at least one of the lids includes the pressure control valve.
An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ, comprising:
- a portable housing, the portable housing including two lids that each form a substantially airtight seal with the portable housing;
- and
- an organ or tissue supporting surface configured to support the organ or tissue within the portable housing while allowing effluent medical fluid to pass through the organ or tissue,
- wherein the portable housing is configured to be received by at least one of a perfusion device, a transporter and a diagnostic device,
- wherein the portable housing includes one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue,
- wherein the portable housing includes at least two devices, each of the at least two devices allows pressure inside the portable housing to be varied and maintained at a desired pressure,
- wherein at least one of the lids includes at least one of the two devices, and
- wherein one of the devices is a pressure control valve, and another device is a membrane.
An apparatus for holding an organ or tissue for at least one of perfusion, storage, diagnosis and transport of the organ or tissue, comprising:
- a portable housing, the portable housing including two lids that each form a substantially airtight seal with the portable housing;
- and
- an organ or tissue supporting surface configured to support the organ or tissue within the portable housing while allowing effluent medical fluid to pass through the organ or tissue,
- wherein the portable housing is configured to be received by at least one of a perfusion device, a transporter and a diagnostic device,
- wherein the portable housing includes one or more openings configured to allow tubing to pass through the openings and be connected to the organ or tissue, and
- wherein the portable housing includes one or more membranes to allow pressure inside the portable housing to be varied and be maintained at a desired pressure,
- wherein each of the lids includes at least one of the membranes.
A method of at least two of perfusion, storage, and transport of an organ or tissue, comprising:
- placing the organ or tissue in a portable housing, the portable housing including more than one lid that forms a substantially airtight seal with the portable housing;
- placing the portable housing containing the organ or tissue in a transporter and transporting the organ or tissue in the portable housing in the transporter;
- without removal of the organ or tissue from the portable housing,
- wherein each of the lids includes a pressure control valve that is configured to restrict the rate at which external pressure changes are transmitted to the inside of the portable housing and to maintain the pressure at a desired pressure.
A method of at least two of perfusion, storage, and transport of an organ or tissue, comprising:
- placing the organ or tissue in a portable housing, the portable housing including more than one lid that forms an airtight seal with the portable housing;
- and
- controlling a rate at which external pressure change is transmitted to the portable housing, the controlling including restricting the rate at which the external pressure change is transmitted to an inside of the portable housing,
- wherein the pressure change transmitted to the portable housing is controlled by a pressure control device, and each of the lids includes the pressure control device.
Dependencies are inferred from the claim text.