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US 7,678,385 B2Granted
Irradiated implantable bone material
AssigneeBiomet Manufacturing, LLC
InventorA. Hari Reddi
Life of this patent
Estimating the term…
Abstract
A method for making an implantable bone material. The method includes providing a bone composition consisting essentially of demineralized human bone, and irradiating the composition at a temperature less than about 0° C.
Claims13
A method for making an implantable bone material, comprising:
- irradiating a bone composition consisting essentially of demineralized human bone, the bone composition having no osteoinductivity prior to the irradiating, at a temperature less than about 0° C., and at a dose of radiation sufficient to increase the osteoinductivity of the bone composition to an Osteoinduction Grading Scale score of at least 2.
A method for improving the osteoinductivity of demineralized bone comprising:
- (a) providing a bone composition consisting essentially of demineralized human bone, the bone composition having no osteoinductivity;
- and
- (b) irradiating the bone composition at a temperature less than about 0° C., at a radiation dose sufficient to produce an increase in the osteoinductivity of the bone composition to an Osteoinduction Grading Scale score of at least 2.
Dependencies are inferred from the claim text.