Fusion proteins of Mycobacterium tuberculosis
AssigneeCorixa Corporation
InventorsYasir Skeiky, Jeff Guderian, Steven Reed
Life of this patent
Estimating the term…
Abstract
The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and nucleic acids encoding such compositions and fusion proteins. The compositions of the invention increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection.
Claims18
A fusion protein comprising a polypeptide having at least 95% identity to the amino acid sequence of SEQ ID NO:16 or SEQ ID NO:18.
A composition comprising a physiological acceptable carrier and a fusion protein that consists of:
- (i) residues 8 to 1154 of SEQ ID NO:16 or
- (ii) residues 8 to 1016 of SEQ ID NO:18.
Dependencies are inferred from the claim text.