Method of substance separation by supercritical fluid chromatography and vapor liquid separator for use therein
AssigneeDaicel Chemical Industries, Ltd.
InventorAkihiro Matabe
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Abstract
A method comprising liquefying a gas to thereby obtain a liquefied gas; injecting a sample into a mobile phase containing a solvent and a supercritical fluid formed from the liquefied gas; passing this mobile phase through a column so that the mobile phase containing desired substance is divided into the solvent and the gas; and separating the desired substance from the solvent, wherein when the pressure of the gas divided from the mobile phase is higher than the pressure of the gas fed for formation of the liquefied gas from gas supply device, the gas divided from the mobile phase is liquefied. Further, there is provided a vapor liquid separator for use in the method.
Claims4
A method of separating a substance by supercritical fluid chromatography, comprising the steps of:
- liquefying a gas to form a liquefied gas;
- injecting a sample comprising a desired substance into a mobile phase comprising a supercritical fluid, formed from the resultant liquefied gas, and a solvent;
- passing the mobile phase into which the sample has been injected through a column for separating the desired substance from the sample;
- and
- dividing the mobile phase comprising the desired substance into the solvent and the gas;
- so that the desired substance is separated from the solvent,
- wherein, in the step of forming a liquefied gas, when a pressure of the gas divided from the mobile phase is higher than a pressure of a gas supplied for formation of the liquefied gas from a gas supply device, the gas divided from the mobile phase is liquefied.
Dependencies are inferred from the claim text.