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US 7,678,143 B2Granted
Ethylene-carboxyl copolymers as drug delivery matrices
AssigneeAdvanced Cardiovascular Systems, Inc.
InventorGene Michal
Life of this patent
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Abstract
A coated stent is provided including a coating composed of one or more co-polymers of ethylene with carboxylic acid wherein the carboxylic acid co-monomer content is 5-50 wt %.
Claims8
A method of coating an implantable medical device, comprising:
- adding a copolymer of an ethylene comonomer with a carboxylic acid comonmer to a solvent system to form a composition;
- mixing a therapeutic drug with the copolymer composition to allow the drug uniformly dispersed in the copolymer composition, wherein the drug concentration is 5% to 20% by weight;
- applying the composition to an implantable medical device;
- and
- allowing the solvent system to evaporate;
- wherein the carboxylic acid comonomer content is 5%-50 wt %.
3 more elements
Dependencies are inferred from the claim text.