Modulators of ATP-Binding Cassette transporters
AssigneeVertex Pharmaceuticals Incorporated
InventorsSara S. Hadida Ruah, Mark T. Miller, Brian Bear, Jason McCartney, Peter D. J. Grootenhuis
Life of this patent
Estimating the term…
Abstract
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Claims6
A compound selected from
A method of increasing CFTR transporter activity comprising the step of contacting said CFTR transporter with a compound selected from
Dependencies are inferred from the claim text.