US 7,665,303 B2 · Method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit

Abstract

The invention described is a method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit. The described invention further includes a method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit wherein the method includes the step of injecting an air pocket into the fluid stream to create the bolus. In addition, the described invention includes a method of measuring the analyte concentration in a bolus of fluid using a pneumatic actuator in a fluid handling circuit. The described invention further includes a method of measuring the analyte concentration in a bolus of fluid using a pneumatic actuator in a fluid handling circuit wherein the method includes the step of injecting an air pocket into the fluid stream to create the bolus.

Claims4

Dependent claims

Method of measuring the analyte concentration in a bolus of fluid using a pneumatic actuator in a fluid handling circuit, said method comprising the steps of:

positioning said fluid in a channel in said fluid handling circuit;
actuating said pneumatic actuator to inject an air into said channel when said fluid is detected by a fill detector;
injecting air from said pneumatic actuator into said channel to form an air pocket upstream from said fill detector;
forming a bolus of said fluid, said bolus having a length which is substantially equal to the distance from said fill detector to said pneumatic actuator;
moving said bolus and said air pocket through said channel until said fluid is positioned over an analyte detector in said channel;
measuring the analyte content of said bolus;
venting said air pocket from said channel.

4 more elements

Dependencies are inferred from the claim text.

Facts

Application

11/095,636Filed 30 Mar 2005 · us provisional application

Priority

31 Mar 2004

Published

US 2005/0220629 A16 Oct 2005

Granted

23 Feb 2010

Term ends

Not estimatedThe source records don’t support an estimate.

Classification13 codes

B01L 3/502784
Characterised by multiphase flow arrangements: specially adapted for droplet or plug flow, e.g. digital microfluidics
G01N 35/1095
Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices: for supplying…
B01L 2200/0605
Fluid handling related problems: metering of fluids
B01L 2200/0673
Fluid handling related problems: handling of plugs of fluid surrounded by immiscible fluid

Method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit

Life of this patent

Method of segregating a bolus of fluid using a pneumatic actuator in a fluid handling circuit

Life of this patent

Abstract

Claims4