Antisense oligonucleotides against VR1
AssigneeGruenenthal GmbH
InventorsJens Kurreck, Volker A. Erdmann
Life of this patent
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Abstract
Antisense oligodeoxynucleotides against VR1, corresponding nucleotide constructs, cells containing said nucleotide constructs, pharmaceutical and diagnostic substances, uses thereof in pain therapy, and methods for diagnosing symptoms related to VR1 and for identifying pain-modulating substances.
Claims32
An anti-sense oligonucleotide 15 to 30 nucleotides in length and comprising the sequence according to one of SEQ ID NOs 2-10, wherein each of SEQ ID NOs 2-10 comprises the sequence according to SEQ ID NO 1.
An anti-sense oligonucleotide 15 to 30 nucleotides in length and comprising
- (1) the sequence according to one of SEQ ID NOs 2-10, or
- (2) a sequence differing from (1) by one different base not located in the sequence according to SEQ ID NO 1.
An anti-sense oligonucleotide consisting of the sequence according to SEQ ID NO 11.
An anti-sense oligonucleotide selected from the group consisting of SEQ ID NOs 1-11.
Dependencies are inferred from the claim text.