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US 7,659,310 B2Granted
Methods of enhancing solubility of agents
AssigneeFormatech, Inc.
InventorsJohn G. Augustine, Kaliappanadar Nellaiappan, Benjamin S. Isaacs, Indu J. Isaacs
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Abstract
This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions.
Claims16
A method of formulating a composition having enhanced solubility of β-Lapachone, said method comprising:
- (A) contacting β-Lapachone with a fatty acid;
- (B) adding a solution of a base to the mixture resulting from step (A), wherein the amount of said base is equimolar to the amount of said fatty acid;
- and (C) steps (A) and (B) result in a composition with enhanced solubility of β-Lapachone.
Dependencies are inferred from the claim text.