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US 7,655,415 B2Granted
IL1RL-1 as a cardiovascular disease marker and therapeutic target
AssigneeThe Brigham and Women's Hospital, Inc.
InventorRichard T. Lee
Life of this patent
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Abstract
This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure.
Claims19
A method, comprising:
- determining the level of an IL1RL-1 molecule in a sample from a subject having or suspected of having a cardiovascular condition by contacting the sample with an agent, wherein the agent specifically binds to the IL1RL-1 molecule, and
- determining the level of at least one other marker in the sample that is predictive of outcome after a myocardial infarction or is increased in heart failure.
Dependencies are inferred from the claim text.