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US 7,648,487 B2Granted
Syringe
AssigneeNipro Corporation
InventorsAkira Ito, Yoshihisa Murai, Takeshi Nizuka, Shin-ich Kawamura, Dai Sutou
Life of this patent
Estimating the term…
Abstract
A syringe coated with a lubricant containing a silicone oil and a fine silica powder on the inner surface of the barrel of the syringe can be used for injection of a surface-active drug solution without oil droplet formation on the inner surface while preventing an increase of the gasket sliding friction.
Claims8
A syringe comprising:
- a barrel,
- a gasket contacting tightly with an inner surface of the barrel,
- a plunger extending from the gasket to a rear end of the syringe for sliding the gasket in the barrel, the inner surface of the barrel being coated with a lubricant containing a straight silicone oil as a main component, a fine silica powder, and a nonionic surfactant, the lubricant containing 5 to 20% by weight of the fine silica powder and 0.1 to 15% by weight of the nonionic surfactant, and
- the syringe being adapted to inject a drug solution containing a drug having a surface activity.
1 more element
A prefilled syringe comprising:
- a barrel,
- a gasket contacting tightly with an inner surface of the barrel,
- a plunger extending from the gasket to a rear end of the syringe for sliding the gasket in the barrel, the inner surface of the barrel being coated with a lubricant containing a straight silicone oil as a main component, a fine silica powder, and a nonionic surfactant, the lubricant containing 5 to 20% by weight of the fine silica powder and 0.1 to 15% by weight of the nonionic surfactant, and
- the syringe being filled with a drug solution containing a drug having a surface activity.
1 more element
Dependencies are inferred from the claim text.