Impedance sensor
AssigneeMassachusetts Institute of Technology
InventorsAimee B. Angel, Ian W. Hunter, Laura L. Proctor, James Tangorra
Life of this patent
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Abstract
A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an impedance sensor. The impedance sensor has an electrode positioned to measure the impedance of a portion of the target area between the needle and the electrode to indicate the depth of penetration of the needle into the target area.
Claims8
A transdermal transport device, comprising:
- a reservoir for holding a substance;
- at least two needles including a first needle and a second needle, each needle having a bore for transporting the substance between the reservoir and a target area of a biological body;
- an impedance sensor to measure electrical impedance of a portion of the target area between the first needle and the second needle, the impedance changing as the needles penetrate through the target area and being indicative of the depth of penetration of the needles into the target area;
- and
- an automated control unit responding to the indicated impedance that monitors the changing impedance through the target area and stops the penetration of the needles into the target area when a desired impedance change has been achieved.
A method to measure penetration into a biological body, comprising:
- penetrating a target area of the biological body with at least two needles including a first needle and a second needle each having a bore for transporting a substance to or from the target area;
- measuring electrical impedance of a portion of the target area between the first needle and the second needle to determine when the needles have penetrated to a desired depth into the target area, the impedance changing as the needles penetrate through the target area;
- and
- stopping the penetration of the needles, using an impedance responsive automated control unit that monitors the changing impedance through the target area, when a desired impedance change has been achieved.
Dependencies are inferred from the claim text.