Antimicrobial coatings
AssigneeUnisearch Limited
InventorsRoger Read, Naresh Kumar, Mark Wilcox, Hua Zhu, Hnas Griesser, Ben Muir, Helmut Thissen, Tim Hughes
Life of this patent
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Abstract
The present invention provides a substrate having a plurality of immobilised furanone moieties associated with at least part of a surface of the substrate. The invention also relates to articles consisting of or comprising such a substrate.
Claims16
A substrate having a plurality of immobilized furanone moieties associated with at least part of a surface of the substrate, wherein the furanone moieties are derived from at least one compound selected from the group consisting of a furanone compound and an analog thereof wherein the furanone moieties are covalently bonded to functional groups on the surface of the substrate;
- and wherein the furanone compound is of the formula
- wherein R1 is a moiety selected from the group consisting of H, halogen, formyl, carboxyl, cyano, ester, amide, alkyl, alkoxy, oxosikyl, alkenyl, alkynyl, aryl and arylalkyl, which moiety may optionally be
- substituted by one more substituents;
- and/or
- interrupted by one or more hetero atoms;
- and/or
- straight chain, branched chain, hydrophobic, hydrophilic and/or fluorophilic;
- R2, R3 and R4 are independently or all H or halogen;
- and
- represents either a double bond or a single bond.
A method of forming an antimicrobial and/or antifungal layer on a substrate including:
- (a) providing a substrate,
- (b) providing at least one furanone compound or an analog thereof;
- (c) treating at least part of the surface of the substrate to introduce functional groups to the surface;
- and;
- (d) reacting the at least one furanone compound or an analog thereof with the functional groups on the treated surface to immobilize the at least one furanone or analog thereof wherein the immobilization on the surface is by means of covalent bonding;
- wherein step (c) is selected from the group consisting of
- corona discharge treatment;
- low pressure plasma treatment;
- introducing reactive aryl azide intermediates to the surface followed by exposure to UV light;
- and
- radiofrequency plasma discharge in the presence of water;
- and wherein the furanone compound is of the formula:
- wherein R1 is a moiety selected from the group consisting of H, halogen, formyl carboxyl, cyano, ester, amide, alkyl, alkoxy, oxoalkyl, alkenyl, alkynyl, aryl or arylalky which moiety may optionally be
- substituted by one or more substituents;
- and/or
- interrupted by one or more hetero atoms;
- and/or
- straight chain, branched chain, hydrophobic, hydrophilic and/or fluorophilic;
- R2, R3 and R4 are independently or all H or halogen;
- and
- represents either a double bond or a single bond.
Dependencies are inferred from the claim text.