Methods and compositions for Mycoplasma pneumoniae exotoxins
AssigneeUniversity of Texas System Board of Regents
InventorsJoel Barry Baseman, Thirumalai Rengasamy Kannan
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Abstract
The present invention provides a Mycoplasma pneumoniae community acquired respiratory distress syndrome (CARDS) toxin, biologically active fragments/domains of the CARDS toxin, antibodies to the CARDS toxin and nucleic acids encoding the CARDS toxin. Also provided are methods of diagnosing, treating and/or preventing infection by Mycoplasma pneumoniae using the compositions provided herein.
Claims4
An isolated nucleic acid encoding a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, and SEQ ID NO:6.
An isolated nucleic acid comprising a nucleotide sequence selected from the group consisting of the nucleotide sequence of SEQ ID NO:8, the nucleotide sequence of SEQ ID NO:10, the nucleotide sequence of SEQ ID NO:11, and the nucleotide sequence of SEQ ID NO:9.
Dependencies are inferred from the claim text.