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US 7,622,558 B2Granted
Antibodies which are directed against the Marburg I polymorphism of factor VII-activating protease (FSAP), and their preparation and use
AssigneeSiemens Healthcare Diagnostics Products GmbH
InventorsHerbert Schwarz, Harald Althaus, Bodo Fischer, Thomas Wissel
Life of this patent
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Abstract
The invention relates to antibodies which are directed against the FSAP Marburg I variant and to their preparation and use, in particular in therapy and diagnosis. The antibodies are characterized by the fact that they bind specifically to the FSAP MR I variant but not to the FSAP wild-type protein or other mutant variants which are characterized by amino acid substitutions at other positions in the FSAP protein.
Claims10
An antibody produced by a hybridoma cell line chosen from DSM ACC2674, DSM ACC2675, DSM ACC2676, DSM ACC2725, and DSM ACC2726.
Dependencies are inferred from the claim text.